Package: POSTm
Type: Package
Title: Phylogeny-Guided OTU-Specific Association Test for Microbiome
        Data
Version: 1.4
Date: 2024-04-17
Authors@R: c(person("Caizhi", "Huang", role = "aut"),
             person("Jung-Ying", "Tzeng", role = "aut"),
             person("Shannon T.", "Holloway", role = c("aut", "cre"),
                     email = "shannon.t.holloway@gmail.com"))
Author: Caizhi Huang [aut], Jung-Ying Tzeng [aut], Shannon T. Holloway
        [aut, cre]
Maintainer: Shannon T. Holloway <shannon.t.holloway@gmail.com>
Description: Implements the Phylogeny-Guided Microbiome OTU-Specific
        Association Test method, which boosts the testing power by
        adaptively borrowing information from phylogenetically close
        OTUs (operational taxonomic units) of the target OTU. This
        method is built on a kernel machine regression framework and
        allows for flexible modeling of complex microbiome effects,
        adjustments for covariates, and can accommodate both continuous
        and binary outcomes.
Depends: methods
Imports: CompQuadForm, ape
Suggests: multtest, rmarkdown, knitr
biocViews:
License: GPL-2
Encoding: UTF-8
LazyData: true
VignetteBuilder: knitr
RoxygenNote: 7.3.1
Collate: 'ACAT.R' 'CKAT.R' 'POSTmData.R' 'distanceMatrix.R'
        'getKernel.R' 'glmFit.R' 'lmFit.R' 'p.adjust.POST.R'
        'plot.POST.R' 'post.R' 'print.POST.R'
NeedsCompilation: no
Packaged: 2026-07-05 02:43:21 UTC; root
Repository: https://sth1402.r-universe.dev
Date/Publication: 2024-04-18 02:35:42 UTC
RemoteUrl: https://github.com/cran/POSTm
RemoteRef: HEAD
RemoteSha: 9a0a0dc8558bfefe7ee22bc52893c92e20a3afcd